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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
42.42
Human Site:
T314
Identified Species:
71.79
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
T314
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
T314
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
T314
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Dog
Lupus familis
XP_538164
1593
182721
T314
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
T314
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Rat
Rattus norvegicus
XP_233081
1594
182711
T314
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
T365
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Chicken
Gallus gallus
XP_420332
1593
182430
T311
K
Q
I
V
R
K
L
T
M
V
V
L
S
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
T309
K
Q
I
A
R
K
L
T
M
V
V
L
P
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
N369
R
E
M
V
R
K
L
N
L
I
Q
T
N
K
K
Honey Bee
Apis mellifera
XP_393587
1354
156054
S239
V
L
G
F
K
Y
C
S
T
V
N
A
T
P
F
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
S274
A
E
T
I
S
T
A
S
M
P
I
M
D
S
R
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
S313
R
Q
Y
A
R
K
M
S
M
A
V
L
A
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
G307
F
E
E
A
N
K
I
G
K
I
N
L
A
A
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
26.6
6.6
13.3
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
86.6
N.A.
73.3
26.6
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
22
0
0
8
0
0
8
0
8
15
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
22
8
0
0
0
0
0
0
0
0
0
0
0
65
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
65
8
0
0
8
0
0
15
8
0
0
0
0
% I
% Lys:
65
0
0
0
8
86
0
0
8
0
0
0
0
8
15
% K
% Leu:
0
8
0
0
0
0
72
0
8
0
0
79
0
0
0
% L
% Met:
0
0
8
0
0
0
8
0
79
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
15
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% P
% Gln:
0
72
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
15
0
0
0
79
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
8
0
0
22
0
0
0
0
58
72
0
% S
% Thr:
0
0
8
0
0
8
0
65
8
0
0
8
8
0
8
% T
% Val:
8
0
0
65
0
0
0
0
0
72
72
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _